WP3 – Deciphering cause-effect relations between gut microbiota and CC
OverviewObjectives: 1/ Develop and implement in vitro models to evaluate the effect of gut microbiota on gut barrier physiology and the immune system. • 2/ Investigate how specific microbial interventions (ghrelinergic microbial strains w/wo phenolic compounds; microbial species, metabolites, and consortia resulting from WP1-2) contribute to control CC in vivo. • 3/ Decipher how circadian clocks are affected upstream by gut microbiota and alter downstream fat expenditure, muscle wasting, lipid homeostasis, and ghrelinergic signalling in a CC mouse model.
Programme: MiCCrobioTAckle
SEEK ID: https://mbt-seek.hki-jena.de/projects/5
Public web page: Not specified
Organisms: No Organisms specified
MBD PALs: No PALs for this Project
Project created: 27th Oct 2025
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Projects: WP1 – Associating native gut microbiome signatures with CC, WP2 – Engineering therapeutic gut microbes for CC, WP3 – Deciphering cause-effect relations between gut microbiota and CC, WP4 – Advancing FMT-based therapies for CC, WP5 – Network, local, and external training, WP6 – Dissemination, exploitation and communication, WP7 – Coordination and project management, Deliverables submitted, Mid-term meeting 20260121
Institutions: MBD, Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
https://orcid.org/0000-0002-2512-7601
Projects: WP3 – Deciphering cause-effect relations between gut microbiota and CC, WP5 – Network, local, and external training, WP6 – Dissemination, exploitation and communication, WP7 – Coordination and project management, Deliverables submitted, Mid-term meeting 20260121, Progress Meeting 20260520
Institutions: Technical University of Denmark, MBD, Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
https://orcid.org/0009-0008-2153-1675
Projects: WP1 – Associating native gut microbiome signatures with CC, WP2 – Engineering therapeutic gut microbes for CC, WP6 – Dissemination, exploitation and communication, WP7 – Coordination and project management, Deliverables submitted, WP5 – Network, local, and external training, WP3 – Deciphering cause-effect relations between gut microbiota and CC, WP4 – Advancing FMT-based therapies for CC, Mid-term meeting 20260121, Progress Meeting 20260520
Institutions: MBD, Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
Projects: WP3 – Deciphering cause-effect relations between gut microbiota and CC, WP5 – Network, local, and external training, WP6 – Dissemination, exploitation and communication, WP7 – Coordination and project management, Mid-term meeting 20260121, Deliverables submitted, Progress Meeting 20260520
Institutions: University College Cork, MBD, Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
Projects: WP3 – Deciphering cause-effect relations between gut microbiota and CC, WP5 – Network, local, and external training, WP6 – Dissemination, exploitation and communication, WP7 – Coordination and project management, Mid-term meeting 20260121, Deliverables submitted
Institutions: University College Cork
Projects: WP3 – Deciphering cause-effect relations between gut microbiota and CC, WP7 – Coordination and project management, WP6 – Dissemination, exploitation and communication, WP5 – Network, local, and external training, Deliverables submitted, Mid-term meeting 20260121, Progress Meeting 20260520
Institutions: University College Cork, MBD, Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
https://orcid.org/0009-0007-6858-7169
At MiCCrobioTAckle, 12 doctoral candidates will participate in an intensive training-through-research program across disciplines and sectors. With academic and industrial partners in the fields of computational biology, microbiology, synthetic biology, clinical, and experimental science, our consortium is prepared to train the Europe’s future leader in microbiota medicine.
Our project offers a unique opportunity to advance microbiota medicine as a new clinical approach to treat diseases and offer ...
Projects: WP1 – Associating native gut microbiome signatures with CC, WP2 – Engineering therapeutic gut microbes for CC, WP3 – Deciphering cause-effect relations between gut microbiota and CC, WP4 – Advancing FMT-based therapies for CC, WP5 – Network, local, and external training, WP6 – Dissemination, exploitation and communication, WP7 – Coordination and project management, Deliverables submitted, Mid-term meeting 20260121, Progress Meeting 20260520
Web page: https://www.miccrobiotackle.eu/
ROR ID: https://ror.org/055s37c97
Department: MBD
Country: 
Germany
City: Jena
Web page: https://www.leibniz-hki.de
ROR ID: https://ror.org/04qtj9h94
Department: Not specified
Country: 
Denmark
City: Kongens Lyngby
Web page: https://dtu.dk
ROR ID: https://ror.org/03265fv13
Department: Not specified
Country: 
Ireland
City: Cork
Web page: https://www.ucc.ie
